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Biotransformation Technology
 
BT is the useful technology for improvement of bioavailability, standardization of the pharmaceutical effect and guiding revelation of the new efficacy of remedy thanks to the transforming of particular structure of effective ingredients in natural substance.

Wellness Korea has the technique know-how for transforming of particular Glycosides and especially, prepare the mass production for Ginsenosides and Isoflavon & Soyasaponin through the technique standardization.



 
Technology scheme
The specific pharmacological ingredient present in the natural product structure by using a bio-transformation technique for biological tools (Microbe / Enzyme), the pharmacological target component is mainly glycosides.
(1) Improve bioavailability of pharmacologically component.
(2) Standardization of pharmacological efficacy
(3) New pharmacological efficacy expression etc.


Applications Progress Situation
Ginsenosides commercialization
Soyasaponin completion of development
 
Application case) Fermented red ginseng
Of the active ingredient of ginseng is Ginsenosides hydrolyzed by intestinal oral ingestion. It is demonstrated that efficacy is absorbed into the body to be removed sugar ingredient. However, our team's research (The Korean Society of Food Science and Nutrition 2014) hydrolysis of Ginsenosides by the intestinal micro flora was found individual differences are very severe.


Individual Differences of hydrolysis for Ginsenosides
 
Ginsenosides present in ginseng or ginseng has significant flaws that are very low bioavailability and pharmacological non-standard due to inter-individual differences in absorption.
Therefore, by applying our specific technology to address these deficiencies Biotransformation high pharmacological potency bioavailability of Ginsenosides have developed a standardized fermented red ginseng.